…Atrial Fibrillation and Atrial Thromboembolism Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and a profound driver of global cardiovascular morbidity and mortality…

…lead V1 and qRS pattern in V6 with QRS duration <120 ms) D: Profound sinus bradycardia (<30 beats/min or sinus pauses ≥3 s) Explanation…

…this demographic on a global scale. Numerous substances possess the potential to induce cardiac arrest or cause profound cardiopulmonary depression. Table 1 delineates substances for…

…of paroxysmal supraventricular tachycardia. Due to its profound pro arrhythmic effects and lack of compelling data regarding morbidity and mortality benefits, digoxin has been ousted…

…an expected fall to below 0.5 × 10⁹/L within 48 hours Profound neutropenia A neutrophil count below 0.1 × 10⁹/L An expected high…

…pain and sensory disturbance. With progression, motor dysfunction develops, followed by profound anaesthesia, paralysis, muscle rigidity and ultimately major tissue loss. Reperfusion after severe or…

…positive hyperacute T waves [15]. Profound ST elevation across multiple leads generally indicates very severe ischemia [15]. A key distinguishing feature of ischemic ST elevation…

…agents to become essential tools for cardiovascular risk reduction, offering profound benefits in major adverse cardiovascular events (MACE), heart failure with preserved ejection fraction (HFpEF…

…diagnosis and management. Over the past decade, the landscape of VT management has undergone a profound paradigm shift. Driven by advanced electroanatomical mapping, high resolution…

…the prognosis. The patient must go to cardiothoracic surgery. In profound shock, very limited decompression may be considered in consultation with a cardiothoracic surgeon. Myocardial…

…or without pain, include sudden loss of consciousness, a confusional state, profound weakness, the appearance of an arrhythmia, evidence of peripheral embolism, or an unexplained…

…with advancing age. Presentations without pain may include: Sudden breathlessness Syncope or sudden loss of consciousness Confusion Profound weakness An arrhythmia Peripheral embolism An ot

…syndromes (NSTE ACS). The division into STE ACS and NSTE ACS has profound implications for management and treatment of patients with acute coronary syndromes. Moreover…

Arrhythmias and arrhythmology Pharmacology & dosing Pharmacokinetic Considerations Relevant to Dosing Amiodarone exhibits highly variable and complex pharmacokinetics that profoundly influence its dosing strategies. The drug…

…Its primary clinical utility in contemporary practice is late line therapy for patients who remain profoundly symptomatic despite optimal neurohormonal blockade and adequate volume control…