…after epicardial flow is restored. Microvascular obstruction may persist despite successful PCI because of endothelial dysfunction, leukocyte and platelet interaction, distal thrombotic debris, cardiomyocyte swelling…

…as no reflow, structural and functional impairments sustain vascular obstruction. Endothelial dysfunction triggers leukocyte and platelet activation, while thrombotic debris may worsen the obstruction. Furthermore…

…also by the vulnerability of the myocardium and coronary microcirculation. Endothelial dysfunction promotes leukocyte and platelet activation and interaction. Thrombotic debris may worsen microvascular obstruction…

…plaque. Upon such damage, the plaque exposes highly thrombogenic materials which activate circulating platelets and coagulation factors, which results in thrombus formation (Figure 1). Disruption…

…the criteria for activation of the massive transfusion protocol. Plasma and platelets: in ongoing bleeding with coagulopathy, or as part of balanced transfusion in massive…

…the communication and the simultaneous delivery of red cells, plasma and platelets. Observational data from trauma suggest a lower overall mortality after such protocols are…

…until the condition has been corrected Marked coagulopathy or thrombocytopenia Routine plasma or platelets are not needed — the INR does not predict bleeding risk in…

…age × AST) / (platelets × √ALT) < 1.3 excludes advanced fibrosis; 2.67 strongly suggests it APRI (AST/upper limit) / platelets × 100 1.0 suggests fibrosis…

…Interference with Platelet Function Test for Heparin Induced Thrombocytopenia (HIT): False negative results in platelet function tests (including HIPA test) for HIT have been reported…

…medication Visual disturbance Persistent severe epigastric pain Pulmonary oedema Thrombocytopenia, with platelets <100 × 10⁹/L Renal insufficiency, with creatinine 1.1 mg/dL Hepatic impairment…