…the criteria for activation of the massive transfusion protocol. Plasma and platelets: in ongoing bleeding with coagulopathy, or as part of balanced transfusion in massive…

…or erosion of a vulnerable (unstable) atherosclerotic coronary plaque. Upon such damage, the plaque exposes highly thrombogenic materials which activate circulating platelets and coagulation factors…

…the communication and the simultaneous delivery of red cells, plasma and platelets. Observational data from trauma suggest a lower overall mortality after such protocols are…

…intravascular coagulation or clinically overt bleeding Refrain until the condition has been corrected Marked coagulopathy or thrombocytopenia Routine plasma or platelets are not needed — the…

…occlusion of a previously atherosclerotic artery. Plaque erosion or rupture exposes thrombogenic material to circulating blood. Platelets adhere, become activated, and aggregate through glycoprotein IIb…

…age × AST) / (platelets × √ALT) < 1.3 excludes advanced fibrosis; 2.67 strongly suggests it APRI (AST/upper limit) / platelets × 100 1.0 suggests fibrosis…

…Interference with Platelet Function Test for Heparin Induced Thrombocytopenia (HIT): False negative results in platelet function tests (including HIPA test) for HIT have been reported…

…medication Visual disturbance Persistent severe epigastric pain Pulmonary oedema Thrombocytopenia, with platelets <100 × 10⁹/L Renal insufficiency, with creatinine 1.1 mg/dL Hepatic impairment…

…or other atherosclerotic vascular disease. Antiplatelet therapy is a central component because platelet activation and aggregation contribute importantly to arterial thrombus formation, recurrent coronary occlusion…

…and platelet aggregation. Because aspirin affects only one pathway of platelet activation, its antiplatelet effect is relatively limited compared with agents that inhibit other platelet…