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Colchicine and Anti-inflammatory Therapy in Coronary Disease

…myocardial infarction COLCOT The COLCOT trial enrolled 4745 patients within 30 days of myocardial infarction. Participants received colchicine 0.5 mg once daily or placebo…

Otoscopy and ear syringing

…membrane — not routinely . The wax has a protective function, and the commonest complication of ear syringing is that someone syringes an ear that did not…

Interpretation of ECG after ROSC (Return of Spontaneous Circulation)

…coronary angiography with the intent of performing PCI. The COACT, PEARL and TOMAHAWK trials studied patients with ROSC who did not display ST segment elevations…

Acute severe asthma in adults: quick reference

…level of risk Ask briefly and to the point: When did the deterioration begin, suddenly or over several days? Which drugs, and how many doses…

A new ECG biomarker for sudden cardiac death

…death, and among those who did, only a minority had a reduced value — the majority of sudden cardiac deaths occur in patients with preserved LVEF…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…factors such as smoking, family history of premature coronary disease, hypertension and hypercholesterolaemia did not fully explain the excess coronary risk. Rheumatoid arthritis RA is…

A Novel Familial Cardiac Arrhythmia Syndrome Identified Using ECG

…in the fifth decade of life in several family members. Imaging studies did not reveal structural cardiac abnormalities, nor coronary artery disease. Another male patient…

Approach to patients with chest pain: differential diagnoses, management & ECG

…When did the patient first note the symptoms and how have the symptoms developed over time? In stable ischemic heart disease, symptoms are typically not…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…did not eliminate it. Angiographic restenosis—defined in the source material as follow up diameter stenosis greater than 50%—occurred in 20–30% of patients…

Early repolarization pattern on ECG (early repolarization syndrome)

…than normal in these patients. However, it is still unknown whether that is actually the case; i.e repolarization may actually not start earlier than…

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