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Colchicine and Anti-inflammatory Therapy in Coronary Disease

…Other anti inflammatory strategies have produced less favourable results. Canakinumab, a monoclonal antibody directed against interleukin 1β, provided proof of concept but was not…

Otoscopy and ear syringing

…membrane — not routinely . The wax has a protective function, and the commonest complication of ear syringing is that someone syringes an ear that did not…

Interpretation of ECG after ROSC (Return of Spontaneous Circulation)

…TOMAHAWK trials studied patients with ROSC who did not display ST segment elevations and randomized them to urgent angiography. These trials did not show any…

Acute severe asthma in adults: quick reference

…the severity by the most serious finding. A patient does not have to meet every criterion in a column. Clinical deterioration or a poor response…

A new ECG biomarker for sudden cardiac death

…term prediction of sudden cardiac arrest. The constraint does not lie in therapy: implantable cardioverter defibrillators (ICDs) are highly effective, terminating well over 99% of…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…family history of premature coronary disease, hypertension and hypercholesterolaemia did not fully explain the excess coronary risk. Rheumatoid arthritis RA is associated with increased carotid…

A Novel Familial Cardiac Arrhythmia Syndrome Identified Using ECG

…life in several family members. Imaging studies did not reveal structural cardiac abnormalities, nor coronary artery disease. Another male patient, with similar ST segment changes…

Approach to patients with chest pain: differential diagnoses, management & ECG

…When did the patient first note the symptoms and how have the symptoms developed over time? In stable ischemic heart disease, symptoms are typically not…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…did not eliminate it. Angiographic restenosis—defined in the source material as follow up diameter stenosis greater than 50%—occurred in 20–30% of patients…

Early repolarization pattern on ECG (early repolarization syndrome)

…than normal in these patients. However, it is still unknown whether that is actually the case; i.e repolarization may actually not start earlier than…

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