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Differential Diagnosis of Chest Pain: A Clinical Overview

…Diagnosis of Chest Pain: A Clinical Overview The evaluation of acute chest discomfort requires a systematic differential diagnosis, as the syndrome associated with ischemic heart…

Chest Pain in the Emergency Department: Diagnostic Pathways

…select a safe disposition and diagnostic strategy. Only a minority of patients presenting with acute chest pain ultimately have ACS; reported rates are generally 5…

Statin Intolerance and Statin-Associated Muscle Symptoms

…Hypothyroidism Vitamin D deficiency Concomitant interacting medications The SLCO1B1 rs4149056 polymorphism is associated with higher statin concentrations and may increase the risk of simvastatin related…

Microvascular Angina and INOCA: Diagnosis with CFR and IMR

…abnormal pain perception in patients without demonstrable ischaemia. The absence of obstructive disease therefore does not establish a benign diagnosis. ANOCA/INOCA is associated with…

Gynaecological examination and cervical smear

Procedurer For many patients a gynaecological examination is associated with a sense of exposure, and technically correct performance is only half the task. The examination…

Reduction of dislocations

…Posterior shoulder dislocation, which is often associated with fracture and requires an orthopaedic surgeon. Dislocation of a native hip (as opposed to a prosthesis) — a…

Exercise stress testing in special patient populations

…is common after myocardial infarction and it is associated with poorer survival. Patients with unstable angina pectoris with low risk (according to TIMI score or…

Management of bradycardia (bradyarrhythmia)

…sleep ( Dickinson et al ). Pronounced sinus bradycardia is frequently associated with hypoxic episodes caused by obstructive sleep apnea. The following bradyarrhythmias are considered normal findings…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…occur at a low level of exertion, or are associated with high event risk. The apparent differences between thresholds reflect different guideline frameworks and clinical…

Brugada syndrome: ECG, clinical features and management

…necessary to develop the disorder. Till now (2016) more than 12 genetic mutations have been associated with the Brugada syndrome. These mutations are located in…

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