…or urticaria triggered by: Acetylsalicylic acid (aspirin). Other non steroidal anti inflammatory drugs (NSAIDs). Other contraindications: Hemophilia. Thrombocytopenia. Active gastric or duodenal ulcers. Liver cirrhosis…

…malignancy and an aortoenteric fistula. Variceal bleeding generally has a higher early mortality than non variceal bleeding [1,2]. Upper gastrointestinal bleeding can present as…

…including: Unstable angina (UA) Non ST elevation myocardial infarction (NSTEMI) ST elevation myocardial infarction (STEMI) This applies to patients undergoing either primary or delayed percutaneous…

…ECG and haemodynamics. Do not wait for troponin. If clinical suspicion persists despite an initially non diagnostic ECG, the ECG must be repeated, particularly with…

…are introduced, although the effect on 24 hour mortality is uncertain and the evidence for non traumatic bleeding is weaker [2,3,4]. Do the…

…or against active cooling to 32–36 °C. The HYPERION result means that active hypothermia is still used in some units with a non shockable…

…for pain). An opioid is rarely the right choice in nociplastic or neuropathic pain, in chronic non cancer pain, or in headache. A failure to…

…carcinoma, squamous cell carcinoma 3–4 mm punch or shave Diagnostic biopsy before definitive surgery Inflammatory dermatosis 4 mm punch from the active edge, not…

…Abdominal obesity is a major driving force. Visceral adipose tissue is metabolically active and produces proinflammatory mediators. Increased free fatty acid flux and impaired insulin…

…4.0 cm 2 . Aortic stenosis is a progressive disease that leads to a gradual reduction in the orifice area. As the area is reduced…