…clinical evaluation, cardiac investigations, genetic counselling and, where appropriate, molecular testing. The approach is particularly relevant to cardiomyopathies, channelopathies, heritable aortopathies, selected congenital heart diseases…

…the nose in one smooth movement — never obliquely upwards towards the eye. 3. Expand it with 5–10 mL of saline through an intravenous cannula…

…adrenaline in anaphylaxis, ceftriaxone, ferric carboxymaltose Rapid, 10–20 min Subcutaneous (SC) Insulin, low molecular weight heparin, GLP 1 analogues, methotrexate, biological agents, adrenaline (second…

…the same broad cholesterol synthesis pathway as statins. The principal molecular target is adenosine triphosphate citrate lyase (ACL), a cytosolic enzyme upstream of 3 hydroxy…

…likelihood of clinically significant EMI is generally low, particularly with bipolar electrocautery performed away from the device and with monopolar electrocautery below the umbilicus. Nevertheless…

…available Low molecular weight heparin Protamine has only a partial effect Unfractionated heparin Protamine Antiplatelet agents Platelet transfusion has weak evidence; discuss with the on…

…Thromboprophylaxis Low molecular weight heparin unless contraindicated Head of the bed 30–45° Stress ulcer prophylaxis During mechanical ventilation, in coagulopathy, or with a history…

…cultures or molecular tests from the suspected focus, but avoid sampling that delays antibiotics 6 Take a targeted history and examine the patient, with particular…

…Low molecular weight heparin, not a DOAC Active cancer A DOAC or low molecular weight heparin. Consider the bleeding risk with gastrointestinal and urogenital tumours…

…TTR) should exceed 70 % Venous thromboembolism 2.0–3.0 Overlap with low molecular weight heparin (LMWH) for at least 5 days Mechanical aortic valve…

…diastolic reserve becomes evident, with a rise in left atrial and pulmonary pressures that contributes to exertional breathlessness and reduced exercise capacity. Multiorgan and comorbidity…

…Genetic, molecular, and acquired factors may interact in its development. PAH may be idiopathic, heritable, drug associated, or associated with conditions such as systemic sclerosis…

…where asymmetric lung sounds are noted, specifically with an absence of sounds on the affected side. Ultrasonography can reveal pneumothorax (highlighted by a lack of…

…with signs of life upon hospital arrival: a retrospective multicenter study. Crit Care 2020; 24:541. Ebo DG, Clarke RC, Mertes PM, et al. Molecular…

…with signs of life upon hospital arrival: a retrospective multicenter study. Crit Care 2020;24:541. Ebo DG, Clarke RC, Mertes PM, et al. Molecular…

…with signs of life upon hospital arrival: a retrospective multicenter study. Crit Care 2020; 24:541. Ebo DG, Clarke RC, Mertes PM, et al. Molecular…

…smaller molecular weight (35 kDa) than cTnT (37 kDa), and a faster release kinetics. This may explain higher peak levels of cTnI compared with cTnT…

…Failure with Reduced Ejection Fraction (HFrEF) is specifically classified by the 2022 AHA/ACC/HFSA and 2021/2023 ESC guidelines as HF with a left…