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Familial and Genetic Screening in Premature Cardiovascular Disease

…risk relative. Across inherited cardiomyopathies, phenotypic expression generally follows a sigmoid pattern over the lifetime. Expression is relatively uncommon in the first decade, rises progressively…

Epistaxis — compression, cautery and anterior nasal packing

…upwards towards the eye. 3. Expand it with 5–10 mL of saline through an intravenous cannula. 4. Tape the drawstring to a gauze pad…

Injection technique — intramuscular, subcutaneous and intradermal

…mL per 3–5 seconds. 7. Withdraw the needle at the same angle and press with a dry swab. Do not massage. Intramuscular — ventrogluteal The…

Bempedoic Acid: Evidence and Clinical Use

…ratio was 0.83, with a 95% confidence interval of 0.72–0.95 and an absolute risk reduction of 2.4%. There was no…

Perioperative Management of Patients with Cardiac Implantable Electronic Devices

…likelihood of clinically significant EMI is generally low, particularly with bipolar electrocautery performed away from the device and with monopolar electrocautery below the umbilicus. Nevertheless…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…available Low molecular weight heparin Protamine has only a partial effect Unfractionated heparin Protamine Antiplatelet agents Platelet transfusion has weak evidence; discuss with the on…

Intensive care parameters

…Thromboprophylaxis Low molecular weight heparin unless contraindicated Head of the bed 30–45° Stress ulcer prophylaxis During mechanical ventilation, in coagulopathy, or with a history…

Neutropenic fever: quick reference for emergency management

…cultures or molecular tests from the suspected focus, but avoid sampling that delays antibiotics 6 Take a targeted history and examine the patient, with particular…

Pulmonary embolism: quick reference for risk stratification and treatment

…Low molecular weight heparin, not a DOAC Active cancer A DOAC or low molecular weight heparin. Consider the bleeding risk with gastrointestinal and urogenital tumours…

Warfarin therapy

…molecular weight heparin (LMWH) for at least 5 days Mechanical aortic valve 2.5–3.5 Some centres use 2.0–3.0 with a…

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