…is today a rare procedure reserved for very serious poisonings in which the patient reaches hospital early. The benefit of both methods falls steeply with…

…As for now, it is sufficient to note that the more myocardium supplied by an artery, the greater the ischemic area in case of occlusion…

…when a modified release preparation is started in an opioid naive patient, or when a conversion between drugs is made without reduction for incomplete cross…

…what was expected. The poison control centre is the authoritative local source for the current indication, dosing, sampling and duration of treatment. International guidelines must…

…women. For European populations, waist circumference above 94 cm in men or 80 cm in women is considered indicative of obesity or excess abdominal adiposity…

…Doppler. It can be illustrated by studying how the frequency of reflected sound waves are modified by the direction of movement of the sound source…

…longer interval for all opioids Obesity Dose according to effect, not according to total body weight Concomitant benzodiazepine A markedly increased risk of respiratory depression…

…altered when atrial activation is modified by cardiac surgery involving atrial tissue, extensive prior radiofrequency ablation, advanced atrial disease, or the use of antiarrhythmic drugs…

…Clinical evidence for cardiovascular benefit CLEAR Outcomes CLEAR Outcomes was a randomized, double blind, placebo controlled study of 13,970 patients at high cardiovascular risk…

…of DAPT unless there is a contraindication, an indication for oral anticoagulation, or an excessive risk of bleeding. The duration and intensity may be modified…

…contraction Active emptying (contraction) of the left atrium Figure 2, a modified Wiggers diagram, provides a comprehensive view of the phases and events during the…

…stunning . This is a protective mechanism since the cessation of contractions leads to a marked reduction in cell metabolism and thus prolongs survival. Myocardial stunning…

…2 ) This formula is excellent for measuring pressure gradients across small openings, such as the valves. Importantly, in the setting of valvular stenosis or regurgitation…

…reduces thrombogenicity, and favourably modifies inflammatory and collagen related components of atherosclerotic plaque. These effects help explain why reductions in cardiovascular events are substantially greater…

…considered a cardiovascular risk modifier, particularly when baseline risk is moderate or near a treatment decision threshold. Failure to account for a high Lp(a…

…modifier" rather than a primary driver of anticoagulation decisions [1] . In both paradigms, a score of ≥2 (excluding sex) is a Class I indication for…

…the number one killer in Western and high income countries for more than half a century, causing approximately 20% of all deaths in these regions…

…BrS is responsible for up to 20% of sudden cardiac deaths in patients without structural heart disease and is the leading cause of SCD in…