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Gastric lavage and activated charcoal

…is today a rare procedure reserved for very serious poisonings in which the patient reaches hospital early. The benefit of both methods falls steeply with…

Factors that modify the natural course in acute myocardial infarction (AMI)

…As for now, it is sufficient to note that the more myocardium supplied by an artery, the greater the ischemic area in case of occlusion…

Opioid therapy in severe pain

…when a modified release preparation is started in an opioid naive patient, or when a conversion between drugs is made without reduction for incomplete cross…

Poisoning: quick reference for antidotes and initial management

…what was expected. The poison control centre is the authoritative local source for the current indication, dosing, sampling and duration of treatment. International guidelines must…

Obesity and Cardiovascular Disease: Assessment and Treatment

…women. For European populations, waist circumference above 94 cm in men or 80 cm in women is considered indicative of obesity or excess abdominal adiposity…

Doppler effect and Doppler echocardiography

…Doppler. It can be illustrated by studying how the frequency of reflected sound waves are modified by the direction of movement of the sound source…

Opioids in acute pain: quick reference for dosing and conversion

…longer interval for all opioids Obesity Dose according to effect, not according to total body weight Concomitant benzodiazepine A markedly increased risk of respiratory depression…

Atrial Flutter: Mechanisms, ECG Recognition and Management

…altered when atrial activation is modified by cardiac surgery involving atrial tissue, extensive prior radiofrequency ablation, advanced atrial disease, or the use of antiarrhythmic drugs…

Bempedoic Acid: Evidence and Clinical Use

…Clinical evidence for cardiovascular benefit CLEAR Outcomes CLEAR Outcomes was a randomized, double blind, placebo controlled study of 13,970 patients at high cardiovascular risk…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…of DAPT unless there is a contraindication, an indication for oral anticoagulation, or an excessive risk of bleeding. The duration and intensity may be modified…

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