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Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…and incompletely absorbed after oral administration, with systemic bioavailability ranging from 25% to 65% and minimal hepatic first pass extraction. Following a single oral dose…

Unstable Angina: Definition and Contemporary Management

…ischemia and infarction Definition and Pathophysiology Unstable angina (UA) is an acute coronary syndrome characterized by myocardial ischaemia occurring at rest or with minimal exertion…

Drugs in the emergency setting

…the neurological outcome in cardiac arrest. High quality compressions with minimal interruptions and early defibrillation are what determine the outcome; drugs are given without pausing…

Spirometry

…4. A maximal inspiration to total lung capacity — rapid, with a minimal pause at the top (< 1 second). 5. A maximal forced expiration : an…

🟠 Inotropes and Vasopressors

…mild inotropic effect. Increases systolic pressure, diastolic pressure and pulse pressure with minimal effect on CO. Minimal chronotropic effect. Increases coronary blood flow. Atrial or…

Acute Coronary Syndrome: Definitions and Initial Triage

…or cardiogenic shock. Features that favour ACS rather than chronic stable angina include sudden symptom onset at rest or with minimal exertion, symptoms lasting at…

Coronary CT Angiography and CAD-RADS Reporting

…non atherosclerotic causes of symptoms should be considered. When plaque is present but stenosis is minimal or mild, symptoms are also unlikely to be caused…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…prompting treatment is ACS. Features that suggest ACS rather than chronic stable angina include: sudden symptoms occurring at rest or with minimal exertion; symptoms lasting…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…refractoriness, and prolong AV nodal refractoriness. Its electrophysiologic effects on the His Purkinje system and ventricular muscle are minimal, except in cases of toxic concentrations…

High-Sensitivity Troponin: 0/1-Hour Rule-In and Rule-Out Algorithms

…symptom initiating evaluation for ACS. Features that increase the likelihood of ACS include: Sudden symptoms at rest or with minimal exertion, lasting at least 10…

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