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Electrical cardioversion

…haemodynamic instability. Digitalis toxicity — a risk of refractory ventricular arrhythmias. Therapeutic digoxin levels, by contrast, are no obstacle. Untreated hypokalaemia or marked electrolyte disturbance; correct…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…syndrome lipid lowering recommendations. Acute coronary syndrome The period immediately following ACS is associated with particularly high risk of recurrent cardiovascular events. Intensive LDL C…

NSTEMI: Risk Stratification and Timing of the Invasive Strategy

…presenting symptoms of NSTEMI. It does identify several clinical manifestations that indicate particularly high risk and should influence the urgency of management: Recurrent or ongoing…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…and the magnitude of LDL C reduction. Thus, even a modest absolute reduction may be clinically important in individuals at high or very high risk…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…from selected populations, frequently with low or intermediate ischemic risk and under representation of patients with STEMI or other very high risk features. Noninferiority studies…

Reduction of dislocations

…compromise or skin tenting — reduce promptly, before radiography. The longer a joint remains dislocated, the harder the reduction becomes and the greater the risk of…

Lipid-Lowering Therapy: Statins as First-Line Treatment

… and A reduction of at least 50% from baseline. In patients who experience a recurrent atherothrombotic or cardiovascular event within 2 years while receiving maximally…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…risk of thrombosis related to the intravascular foreign body. First generation DES, particularly sirolimus and paclitaxel eluting devices, were associated with increased late and very…

Risk factors for sudden cardiac arrest

…Strong risk factors serve as useful predictors in prediction models. Targeting risk factors has been very successful in the primary and secondary prevention of atherosclerotic…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…refractory to guideline directed medical therapy, occur at a low level of exertion, or are associated with high event risk. The apparent differences between thresholds…

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