…gravity and slow movement; those that fail usually do so because the patient tenses up with pain, or because the operator pulls harder rather than…

…abnormal often abnormal abnormal, possibly flail CW profile mitral regurgitation weak variable dense Shape CW profile mitral regurgitation parabolic variable early peak, triangular Size left…

…used in younger adults, whereas a markedly frail 65 year old may require the more cautious approach generally applied to older patients. Frailty is characterized…

…interpreted as specialist investigations. Both fail more often for practical than for medical reasons: the cuff is in the wrong place, the electrodes come off…

…on the drug chart. Glucose targets on the ward Situation Target plasma glucose : : Most inpatients 6–10 mmol/L Frail older people, a short expected…

…the investigation, not the end. In a frail older patient an apparently small insult — sleep deprivation, urinary retention or a new sedative drug, for example…

…important therapeutic objectives. Evidence from randomized trials is often less applicable to very frail or multimorbid patients because these groups have historically been underrepresented. Consequently…

…Books that claim to make it "simple" can provide a quick entry point but fail to delve into the crucial depths needed for clinical practice…

…a dose of 30 ml/kg. Should fluid resuscitation fail to maintain a mean arterial pressure (MAP) above 65 mmHg, consider the initiation of vasopressor…

…This is also a normal finding. Abnormal (pathological) causes of sinus bradycardia In all other situations, sinus bradycardia should be regarded as a pathological finding…

…compressions ineffective. For instance, a traumatic hemorrhage can deplete intravascular volume to such an extent that chest compressions fail to generate stroke volumes. Consequently, addressing…

…acute stroke to identify large vessel occlusion, dissection or other vascular pathology CT perfusion Used with an unclear time of onset, a late time window…

…intravenous) Loading dose by weight, maintenance dose by renal function and drug concentration Gentamicin and other aminoglycosides A single dose initially. If treatment is continued…

…moderate to severe frailty, or very old or frail patients who may not tolerate rapid blood pressure reduction. Initial Combination Therapy General Strategy For most…

…MINOCA accounts for approximately 1–14% of ACS presentations in different series and approximately 5–10% of patients presenting with myocardial infarction in other reports…

…for evaluating the success of TdP treatment or detailed step by step algorithms for alternative therapies when initial pharmacological approaches fail to suppress the arrhythmia…

…of cervical spine injury, in which scenario head tilt chin lift should only be used if other methods fail to open the airway. Figure 1…

…DEFINE FLAIR · iFR SWEDEHEART · 5 yr pooled analysis · VALIDATE RFR Coronary Flow Reserve (CFR) & Index of Microcirculatory Resistance (IMR) CFR: ratio of hyperemic to resting…

…as ejection fraction may provide easily obtained parameters, but fail to provide important insights into left ventricular mechanics. Regional differences in contractile function are of…