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Oxygen therapy

…resorption. Other conditions in which high flow oxygen is given irrespective of the saturation according to international guidelines are decompression sickness and sickle cell crisis…

Cryotherapy of skin lesions

…cell carcinoma — these can be treated with cryotherapy by an experienced practitioner in selected cases, but surgery is the standard. Dark skin: a risk of…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…of acute myocardial ischaemia, electrocardiographic findings, cardiac biomarkers, imaging, angiography, and, occasionally, pathological examination. Pathologically, infarction represents myocardial cell death caused by prolonged ischaemia. The…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…radiotracers emit gamma photons directly. These gamma rays are detected by gamma cameras to create tomographic images of the left ventricle. In PET (Positron Emission…

The ECG in assessment of myocardial reperfusion

…by rapid normalization of myocardial cell membrane potentials in the ischemic area. Myocardial cells are capable of normalizing their membrane potentials immediately as oxygen becomes…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…foam cells, and a thin fibrous cap. Disruption of the cap exposes the lipid core and extracellular matrix to circulating blood. Tissue factor within the…

The QRS complex: ECG features of the Q-wave, R-wave, S-wave & duration

…one contractile cell to another, starting in the endocardium and heading towards the epicardium. As evident from Figure 7 , the vector of the ventricular free…

Care after return of spontaneous circulation (ROSC)

…state, or brain death. The cause of brain injuries is anoxic cell death, continued dysfunction in cerebral blood flow (autoregulation) after ROSC and cerebral hypoperfusion…

The 3-phase model of sudden cardiac arrest

…50% of the ATP remained. Figure 1 . Myocardial ATP concentration after induction of ventricular fibrillation (cardiac arrest). As ATP concentration declines, critical cell functions cease…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

… abundant foam cells and macrophages; a thin fibrous cap; positive remodelling; neovascularization; intraplaque haemorrhage; adventitial inflammation; spotty calcification. Nevertheless, the presence of these features does…

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Clinical ECG Interpretation

The ECG book is a comprehensive e-book, covering all aspects of clinical ECG interpretation, and will take you from cell to bedside.

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