…As the inflammation and deposition of lipids progress, an atherosclerotic plaque forms in the wall of the artery. Such atherosclerotic plaques start building up early…

…overdose. Tumour lysis syndrome appears as an indication in older protocols but is no longer routinely recommended — alkaline urine increases the precipitation of calcium phosphate…

…of the drug's pharmacological effects are produced during its first passage through the circulation. Due to this rapid clearance, adenosine must be administered as…

…on the extracytoplasmic face of the alpha subunit of the Na+ K+ ATPase. This binding is entropically driven and preferentially occurs after the phosphorylation of…

…in the LDL receptor gene, LDLR, which account for most cases. Variants in APOB that impair apolipoprotein B binding to the LDL receptor. Gain of…

…Stimulation of beta receptors increases inotropy and chronotropy by elevating intracellular cyclic adenosine monophosphate (cAMP) and calcium, as well as through the direct activation of…

…low. Notably, specificity increases when the septum bulges into the left ventricle (i.e. septal bulging ). Bedside echocardiography allows for immediate recognition of tamponade. Typically…

…Insert the speculum under vision, to a maximum of about 8 mm. 5. Follow a systematic order: the skin of the ear canal → the…

…in the cortisol assay and can be given as steroid cover during the test Oestrogen and the combined oral contraceptive These raise cortisol binding globulin…

…100 mg/day during the third trimester of pregnancy. Dosage Acute myocardial infarction: Initial loading dose: 300–500 mg as soon as possible after symptom…

…suggestive of myocardial ischemia. It is also recommended that leads V7, V8 and V9 be connected to the patient, as these leads may reveal the…

…recording of mitral valve flow during diastole. (a) = active atrial filling; (b) = increased atrial pressure due to bulging of mitral valve into the…

…radiotracers emit gamma photons directly. These gamma rays are detected by gamma cameras to create tomographic images of the left ventricle. In PET (Positron Emission…

…side of the tricuspid annulus) function as atrium and becomes dilated. The anterior leaflet is usually larger. It may be fenestrated and swing into the…