…third trimester of pregnancy. Dosage Acute myocardial infarction: Initial loading dose: 300–500 mg as soon as possible after symptom onset. Prophylaxis against cardiovascular complications…

…age 65, and concomitant drug/alcohol use. Some studies suggest HAS BLED has comparable or slightly superior predictive capability for major bleeding compared to ATRIA…

…INR), older age, drugs predisposing to bleeding and alcohol use. A high bleeding risk score should prompt correction of modifiable risk factors and closer surveillance…

…Moreover, the HAS BLED score has been found to be predictive of intracranial hemorrhage, which is considered the most devastating complication related to anticoagulation use.

…with ECG may reveal atrial fibrillation. Unfortunately, atrial fibrillation is too often discovered first at hospital admission due to its complications (stroke, thromboembolism, heart failure…

…with readiness for respiratory support. 5. Treatment of the alcohol use disorder and planned follow up , not merely detoxification. Benzodiazepines reduce the severity of withdrawal…

…Blood alcohol concentration generally peaks 10–60 minutes after ingestion. Elimination follows zero order kinetics at low to moderate concentrations and first order kinetics at…

…is decided before the needle goes in: the choice of site, the use of ultrasound throughout the puncture, and maintaining maximal barrier precautions without shortcuts…

…osteoarthritis related joint disease. Contraindications Infection of the skin or soft tissues over the puncture site — use another approach or refrain. Bacteraemia without suspicion of…

…Withdraw slowly. • Simultaneous use of tricyclic antidepressants reduces the effect of clonidine. • Clonidine increases the CNS depressive effects of alcohol and sedatives. Clonidine doses and…