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Heart Failure with Reduced Ejection Fraction (HFrEF)

…failure is staggering, affecting an estimated 64 million individuals worldwide. In developed nations, the prevalence of HF is approximately 1–2% in the general adult…

Drugs in the emergency setting

Procedurer The doses below apply to adults unless otherwise stated, and paediatric doses are given per kilogram with the stated maximum. Always check against the…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…heart failure, digoxin improves hemodynamics without increasing heart rate or decreasing blood pressure, making it a consideration for patients with low blood pressure secondary to…

Opioids in acute pain: quick reference for dosing and conversion

…half the adult dose and lengthen the interval Liver failure A reduced dose and a longer interval for all opioids Obesity Dose according to effect…

Opioid therapy in severe pain

…turned has not finished being titrated. Expect an opioid naive adult to need 5–15 mg of morphine in total. If more than that is…

Lipoprotein(a): Measurement and Clinical Implications

…heart failure, and weakest with ischaemic stroke and cardiovascular or all cause mortality. Risk rises gradually from approximately 30 mg/dL (62 nmol/L) to…

🟠 Ticagrelor (Brilinta, Brilique)

…in adult patients with acute coronary syndrome (ACS) or a prior heart attack and a high risk of developing an atherothrombotic event. Contraindications Hypersensitivity to…

Urinary alkalinisation

…kg intravenously in symptomatic salicylate poisoning. For an adult this corresponds to the order of 100–200 mL of the 50 mg/mL solution. 6…

Adenosine for tachyarrhythmias (AVNRT, AVRT, NCT)

…is required in renal failure or renal replacement therapy. Pediatric patients Body weight < 50 kg: Initial dose: 0.05 to 0.1 mg/kg…

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…activity–in a young adult with T wave inversions in V1–V4, or other ECG changes (see below) should lead to a suspicion of ARVC…

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