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Wound suturing

…5 mm often do better with adhesive strips, tissue adhesive or a dressing alone. Contraindications Primary closure must be avoided or considered carefully in: Bite…

Transcutaneous and transvenous pacing

…pacing: burns or wounds in the area where the pads would go. Transvenous pacing: the relative contraindications are the same as for a central venous…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…antithrombotic surface, and control the adhesion and migration of inflammatory cells. Dyslipidaemia, cigarette smoking, hypertension, diabetes mellitus and other adverse influences disturb these functions. The…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…

Microvascular Angina and INOCA: Diagnosis with CFR and IMR

…or cause abnormal vasoconstriction of coronary arterioles. Structural and functional mechanisms may coexist. The formal diagnostic construct for MVA incorporates four components: Symptoms suggestive of…

Heart Failure with Preserved Ejection Fraction (HFpEF)

…pressures. Epidemiology and risk factors HFpEF has reached epidemic proportions, now accounting for over 50% of all incident heart failure cases globally [5] . Registry data…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…The transition from a quiescent plaque to a highly thrombogenic surface occurs via three primary mechanisms: Plaque Rupture: Accounting for 60 70% of ACS presentations…

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