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Wound suturing

Procedurer The result of a repair is determined before the first needle goes in. A wound that has not been irrigated clean, has not been…

Transcutaneous and transvenous pacing

…bundle branch block in acute anterior infarction, and before drugs or procedures with a known risk of bradycardia. Transvenous pacing is chosen when the need…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…Endothelial and smooth muscle cells normally regulate vascular tone, preserve an antithrombotic surface, and control the adhesion and migration of inflammatory cells. Dyslipidaemia, cigarette smoking…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…bind to the upregulated adhesion molecules, transmigrate into the intima via diapedesis, and differentiate into tissue macrophages under the influence of macrophage colony stimulating factor…

Microvascular Angina and INOCA: Diagnosis with CFR and IMR

…promote the release of adhesion molecules, inflammatory cytokines, and vasoconstricting mediators, producing abnormal vascular responses and potentially increasing the future risk of obstructive coronary disease…

Heart Failure with Preserved Ejection Fraction (HFpEF)

…chronic, systemic proinflammatory state. This circulating inflammation leads to coronary microvascular endothelial dysfunction, characterized by the upregulation of adhesion molecules (e.g., VCAM 1) a

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…Regardless of the initiating mechanism, the exposure of thrombogenic material triggers a rapid cascade of platelet adhesion (mediated by von Willebrand factor and Glycoprotein Ib…

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