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Colchicine and Anti-inflammatory Therapy in Coronary Disease

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiology Atherosclerosis and acute coronary syndromes have important inflammatory components. Inflammation contributes to atherothrombosis through activation of…

Lipid-Lowering Therapy: Statins as First-Line Treatment

…in reducing major cardiovascular events. Acute coronary syndromes The period immediately after ACS is particularly vulnerable, with recurrent cardiovascular events concentrated early after discharge. Consequently…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…

Pharmacologic agents in myocardial perfusion imaging

…Baseline ECG abnormalities rendering ST T interpretation difficult, including left bundle branch block (LBBB) or pacemaker rhythms. Atrial fibrillation or atrial flutter Patients on medications…

Cardiovascular effects of COVID-19 (Coronavirus Disease 2019)

…Guo et al also report a significant association between troponin T levels and C reactive protein (CRP) and N terminal pro B type natriuretic peptide …

Acute vertigo: quick reference for HINTS and differential diagnosis

…acute dizziness with spontaneous nystagmus: consider HINTS plus, but only if the examiner is trained. Brief attacks triggered by the position of the head relative…

Levosimendan (Simdax, Simendan) in acute heart failure

…be counteracted with simultaneous administration of norepinephrine. All patients with severe acute heart failure who receive levosimendan should be monitored invasively (e.g. arterial line…

Peripheral venous cannula and intraosseous access

Procedurer In acute circulatory failure it is not the number of cannulae that matters but the flow per unit time . A large bore, short cannula…

The left ventricle in myocardial ischemia and infarction

…a thick layer that much of it may receive oxygen directly from the blood within the atrial cavity. The left ventricle is considerably thicker and –…

Anaphylaxis: quick reference for emergency management

…ones [5]. For acute clinical use the following simplification can be used: Grade Clinical picture Management : : : Mild allergic reaction Skin or mucosa only, stable breathing…

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