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Acute Limb Ischaemia: Recognition and Urgent Management

…obstruction may result from progression of peripheral arterial disease, cardiac or aortic embolisation, acute aortic dissection, thrombosis of a graft or aneurysm, popliteal artery entrapment…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…on circulating thrombotic and fibrinolytic factors. Plaque erosion Plaque erosion is increasingly recognized and is present in at least one third of acute coronary syndromes…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…events in the setting of a stent thrombosis or restenosis. Type 1 myocardial infarction Definition and pathophysiology Type 1 MI results from acute coronary atherothrombosis…

Type 2 Myocardial Infarction: Mechanisms and Management

…smooth muscle cell dysfunction, and dysregulation of sympathetic innervation), coronary embolism, and spontaneous coronary artery dissection with or without intramural haematoma. Spontaneous coronary artery dissection…

Indications and contraindications for myocardial perfusion imaging

…heart failure Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis Acute myocarditis or pericarditis Acute aortic dissection Physical disability that precludes safe and adequate…

Myocardial Infarction with Non-Obstructive Coronary Arteries: Causes, Work-up and Management

…Definition and clinical concept Myocardial infarction with non obstructive coronary arteries (MINOCA) describes a clinical presentation in which the patient has symptoms suggestive of acute…

Pulmonary Embolism (PE)

…Epidemiology of pulmonary embolism Venous thromboembolism (VTE) is the third leading cardiovascular cause of death worldwide. Only stroke and acute myocardial infarction are more common…

ST-Segment Elevation Myocardial Infarction: Diagnosis and ECG Criteria

…underlying process usually involves acute thrombotic obstruction of an epicardial coronary artery. A vulnerable atherosclerotic plaque and thrombogenic blood interact to initiate and extend thrombosis…

Indications, Contraindications, and Preparations for Exercise Stress Testing

…stenosis – due to risk of syncope, ischemia, and arrhythmias Endocarditis – due to risk of embolization Deep venous thrombosis – due to risk of embolization Relative contraindications…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…higher target Doses in venous thromboembolism Treatment doses in deep vein thrombosis and pulmonary embolism differ from the atrial fibrillation doses and include an initial…

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