…INR before the first dose. A raised baseline value suggests liver disease or vitamin K deficiency and must be investigated before treatment is started. 2…

…not exclude iron deficiency in the presence of inflammation Transferrin saturation 15–50 % < 15 % indicates iron deficiency whatever the ferritin Vitamin B12 150–650…

…infection Renal or hepatic impairment Hypothyroidism Vitamin D deficiency Concomitant interacting medications The SLCO1B1 rs4149056 polymorphism is associated with higher statin concentrations and may increase…

…tamoxifen, lithium, thiazide diuretics, D vitamin and calcium overdose. ECG changes due to hypercalcemia Common ECG changes Shortened QT interval. Lengthened QRS duration. Bradycardia may…

…is rarely needed with DOACs. Reversal in major bleeding Drug Reversal : : Warfarin Prothrombin complex concentrate (dose by INR and weight) plus vitamin K 10 mg…

…leethanol Heavy metals Chelating substances Ionizing radiation Potassium iodide Iron Deferoxamine Isoniazid Pyridoxine (Vitamin B6) Methanol Fomepizoleethanol Methemoglobin forming substances Methylene blue Methotrexate Leucovorin (folinic…

…is not prolonged Fulvestrant FULVESTRANT Fulvestrant NA no no AQUASOL A VITAMIN A PALMITATE VITAMIN A PALMITATE NA sp ambiguous hypotension(Pediatric Use) mild BAL…

…of adrenal insufficiency. Prophylaxis during longer corticosteroid treatment Risk Action : : Osteoporosis Calcium and vitamin D. A bisphosphonate with longer treatment and risk factors, according to…

…renal insufficiency, therapeutic interventions with tamoxifen or lithium, thiazide administration, and over supplementation of calcium and vitamin D. ECG in hypercalcemia Typical ECG changes: Shortened…