…INR before the first dose. A raised baseline value suggests liver disease or vitamin K deficiency and must be investigated before treatment is started. 2…

…deficiency whatever the ferritin Vitamin B12 150–650 pmol/L Grey zone 150–250: add homocysteine or methylmalonic acid Folate 7 nmol/L Electrolytes and…

…or hepatic impairment Hypothyroidism Vitamin D deficiency Concomitant interacting medications The SLCO1B1 rs4149056 polymorphism is associated with higher statin concentrations and may increase the risk…

…tamoxifen, lithium, thiazide diuretics, D vitamin and calcium overdose. ECG changes due to hypercalcemia Common ECG changes Shortened QT interval. Lengthened QRS duration. Bradycardia may…

…is rarely needed with DOACs. Reversal in major bleeding Drug Reversal : : Warfarin Prothrombin complex concentrate (dose by INR and weight) plus vitamin K 10 mg…

…L carnitine (limited evidence) Warfarin Vitamin K Fresh frozen plasma Prothrombin complex concentrate Actions in suspected poisoning and cardiac arrest Promptly contact the closest intensive…

…is not prolonged Fulvestrant FULVESTRANT Fulvestrant NA no no AQUASOL A VITAMIN A PALMITATE VITAMIN A PALMITATE NA sp ambiguous hypotension(Pediatric Use) mild BAL…

…and about the symptoms of adrenal insufficiency. Prophylaxis during longer corticosteroid treatment Risk Action : : Osteoporosis Calcium and vitamin D. A bisphosphonate with longer treatment and…

…renal insufficiency, therapeutic interventions with tamoxifen or lithium, thiazide administration, and over supplementation of calcium and vitamin D. ECG in hypercalcemia Typical ECG changes: Shortened…