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SGLT2 Inhibitors for Cardiovascular and Renal Protection

…T2DM with established cardiovascular disease or high cardiovascular risk T2DM with chronic kidney disease Heart failure with reduced ejection fraction (HFrEF), with or without diabetes…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…heart failure with preserved ejection fraction (HFpEF), chronic kidney disease (CKD), and peripheral artery disease (PAD). Figure 1 (below) shows weight loss effects of novel…

Heart Failure with Preserved Ejection Fraction (HFpEF)

…type 2 diabetes mellitus, chronic kidney disease (CKD), sedentary lifestyle, and atrial fibrillation (AF) [5] . Unlike HFrEF, where epicardial ischemic heart disease and myocardial infarction…

ACE Inhibitors: Initiation, Titration and Creatinine Monitoring

…a cornerstone in the management of cardiovascular disease, heart failure, and chronic kidney disease (CKD). These agents interfere with the renin angiotensin aldosterone system (RAAS…

Atrial fibrillation: ECG, classification, causes, risk factors & management

…heart failure, congenital heart disease, diabetes mellitus (both type 1 and type 2), obesity, smoking, obstructive sleep apnea and chronic obstructive pulmonary disease (COPD). Moreover…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…possible stent thrombosis for clinical research and outcome assessment. Predisposing factors Domain Factors associated with stent thrombosis Clinical Acute myocardial infarction, diabetes mellitus, renal failure…

Diabetic ketoacidosis and hyperosmolar hyperglycaemic state: quick reference

…diagnosis of DKA requires three components: diabetes or hyperglycaemia, ketosis and metabolic acidosis. A very high glucose value is no longer required [1]. Diabetic ketoacidosis…

Inpatient insulin therapy: quick reference

…or long acting) Covers fasting glucose production Everyone with type 1 diabetes, always, including while fasting. Many with type 2 Mealtime insulin (rapid acting) Covers…

Primary Aldosteronism: Screening and Management

…production Familial forms include familial hyperaldosteronism type 1, formerly termed glucocorticoid remediable aldosteronism, and other familial forms associated with adrenal adenoma or bilateral adrenal hyperplasia…

Unstable Angina: Definition and Contemporary Management

…are reported more frequently in females, older adults and people with diabetes. Ischaemic heart disease may also present without prominent discomfort through heart failure, arrhythmias…

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