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Cryotherapy of skin lesions

Procedurer Cryotherapy destroys tissue through intracellular ice crystal formation and through microvascular thrombosis in the treated area. The method is quick, cheap and requires no…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…typically involves a thin, collagen poor fibrous cap overlying a large lipid core with many macrophages, resulting in a red, fibrin rich thrombus. In contrast…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…susceptible to disruption and thrombosis. Typical features include a lipid rich core, a thin fibrous cap, macrophage and foam cell accumulation, expansive or positive remodelling…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…Rupture: Accounting for 60 70% of ACS presentations, plaque rupture typically occurs in thin cap fibroatheromas (TCFAs). These vulnerable plaques possess a massive necrotic lipid…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

Cardiology Myocardial ischemia and infarction Definition and pathophysiology Atherosclerosis is a chronic, inflammatory disease of the arterial wall in which lipid accumulation, vascular cell dysfunction…

Intravascular Imaging: IVUS and OCT for PCI Optimisation

…Virtual histology IVUS has also been used to identify thin cap fibroatheroma, a plaque phenotype associated with subsequent major adverse cardiovascular events in observational studies…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…plaque to a high risk, vulnerable plaque (VP)—specifically the thin cap fibroatheroma (TCFA)—is driven by an imbalance between matrix synthesis and degradation. Histologically…

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