…anticoagulants (DOACs) are contraindicated. Antiphospholipid syndrome, particularly triple positive disease or after an arterial event, where DOACs have proved inferior. Atrial fibrillation with marked renal…

…other extracorporeal therapy (requires a large bore dialysis catheter, not an ordinary triple lumen catheter). Measurement of central venous pressure and central venous oxygen saturation…

…infection or gastroenteritis at home Double or triple the oral daily dose during the days of illness (the patient's sick day rules) Vomiting or…