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Pericardiocentesis

…Procedure Choice of access The ultrasound, not tradition, determines the site. Scan subxiphoid, parasternally and apically, and choose the site where the rim of fluid…

Causes of sudden cardiac arrest

…the presence of arrhythmogenic substrates. A substrate is defined as a physiological or anatomical factor that can trigger or sustain arrhythmias, such as necrotic tissue…

Ejection fraction (EF): Physiology, Measurement & Clinical Evaluation

…or supranormal ejection fraction , despite manifest heart failure and severe symptoms. These individuals exhibit pronounced hypertrophy, resulting in a reduction of ventricular volume and subsequently…

Diuretic Strategy and Decongestion in Heart Failure

…the full range of left ventricular ejection fraction and may result from systolic dysfunction, diastolic dysfunction, or both. The clinical consequences of extracellular volume expansion…

Ventricular Tachycardia

…decision making. Structural Heart Disease (SHD): Accounting for approximately 90% of all VT presentations, SHD provides the macroscopic architectural abnormalities necessary for arrhythmogenesis. Ischemic heart…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…cardiac MRI) are frequently necessary. Ischemic cardiomyopathy should be suspected if there is significant stenosis ( 75% luminal obstruction) of the left main coronary artery (LAD…

Ischemic Cardiomyopathy: Myocardial Viability Assessment and Revascularization

…However, the presumed relationship between viability, recovery of ejection fraction, and survival has been challenged by randomized trials. Relationship between viability and LV recovery Observational…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…with preserved ejection fraction (HFpEF), chronic kidney disease (CKD), and peripheral artery disease (PAD). Figure 1 (below) shows weight loss effects of novel multi agonists…

Alcohol and Cardiovascular Disease

…Direct toxic effects on cardiomyocytes Disruption of intracellular signalling and protein synthesis Electrical channelopathies Oxidative stress Cellular apoptosis and necrosis Progressive structural remodelling Alcohol associated…

Left Bundle Branch Block: ECG criteria and clinical implications

…For patients with LBBB and a left ventricular ejection fraction (LVEF) $< 35%$, the implantation of a defibrillator or a CRT D is indicated…

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