…of more efficacious agents with wider therapeutic to toxic windows, and its routine use in adult patients is generally discouraged. However, it retains a specific…

…of supraventricular tachycardias (SVTs), usually within 30 seconds. Doses higher than 18 mg are unlikely to revert a tachycardia and should not be used. Specific…

…Interactions Pharmacodynamic interactions Anticoagulants, thrombolytics, or other platelet aggregation inhibitors: Salicylates inhibit platelet function and enhance the effect of anticoagulants, increasing bleeding risk. Monitor coagulation…

…males and 40 g daily in females as capable of causing cardiomyopathy. Several mechanisms contribute: Direct toxic effects on cardiomyocytes Disruption of intracellular signalling and…

…This side effect lasts a few seconds. Case reports have indicated that the risk of high degree AV block and ventricular arrhythmias is greater in…

…with a relatively clear level of consciousness and preserved orientation 12 to 48 hours Withdrawal seizures, usually generalised tonic clonic and sometimes several within a…

…effects of contrast exposure and other ischaemic or nephrotoxic stresses. The kidney is particularly vulnerable to toxic injury because of its high blood flow and…

…or fumes. Preoperative assessment before thoracic or upper abdominal surgery in a patient with known lung disease. Follow up of treatment effect and of disease…

…Toxic and infiltrative causes are increasingly recognized. The burgeoning field of cardio oncology has highlighted the cardiotoxic effects of anthracyclines, HER2 inhibitors (trastuzumab), and immune…

…interval can cause serious arrhythmias and sudden cardiac death. QT prolongation can precipitate torsades de pointes, a specific form of polymorphic ventricular tachycardia characterized by…