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Hypertensive crisis: quick reference for acute blood pressure lowering

…Systemic sclerosis, kidney disease, autoimmune disease or previous thrombotic microangiopathy. Antidepressants can affect the blood pressure in several ways. Monoamine oxidase inhibitors can cause a…

🟠 Ticagrelor (Brilinta, Brilique)

…Thrombotic Thrombocytopenic Purpura (TTP): In very rare cases, TTP has been reported with ticagrelor treatment. TTP is characterized by thrombocytopenia and microangiopathic hemolytic anemia associated…

Hypertensive Emergency and Urgency: Differentiation and Treatment

…severe hypertension. The decision to lower BP in acute stroke requires attention to the type of stroke and the possibility of thrombolytic treatment. Cardiac and…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…It is a PCI related myocardial infarction when angiography or autopsy documents thrombosis and the diagnostic criteria used for type 1 myocardial infarction are fulfilled…

🟠 TIMI Risk Score for NSTEMI and unstable Angina

All patients with NSTE ACS (NSTEMI or unstable angina) are treated similarly with respect to anti ischemic and anti thrombotic drugs. Management must, however, be…

Fourth Universal Definition of Myocardial Infarction: Types 1–5

…the past century. Initial post mortem observations in the late 19th century first linked thrombotic occlusion of a coronary artery with myocardial necrosis. Although early…

Leg ulcers — wound debridement and compression therapy

…< 30 mmHg. Decompensated heart failure — compression of both legs acutely increases preload. Untreated deep vein thrombosis in the acute phase. Septic phlebitis, ongoing soft…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…syndrome (ACS), DAPT is used to reduce recurrent myocardial infarction, stent thrombosis and other ischemic events after coronary angiography, percutaneous coronary intervention (PCI), or medical…

No-Reflow Phenomenon During Percutaneous Coronary Intervention: Prevention and Treatment

…exceeding those seen with native vessel PCI. Mechanisms The principal mechanism is distal embolization of atheromatous and thrombotic material. Plaque or thrombus may be dislodged…

ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…zone. Coronary Occlusion and Myocardial Injury STEMI generally results from abrupt reduction in coronary blood flow caused by thrombotic occlusion of a previously atherosclerotic artery…

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