… raised by anaemia, age and pregnancy Procalcitonin < 0.25 µg/L Supports a bacterial aetiology; used to guide antibiotic therapy Glucose and lipids Test…

…This distinction supports a risk based approach because cardiovascular benefit from blood pressure reduction may also occur in selected people whose pressure is elevated but…

…major therapeutic target. This concept is clinically relevant because cardiovascular risk may persist despite appropriate lipid lowering and other guideline directed therapies. Anti inflammatory treatment…

…mL supports the diagnosis Structural or functional cardiac abnormality Evidence such as increased left atrial size, left ventricular hypertrophy or abnormal LV filling supports the…

Cardiology Pharmacology & dosing Definition and therapeutic rationale Inclisiran is a liver directed small interfering RNA (siRNA) designed to reduce production of proprotein convertase subtilisin/kexin…

…based on randomized controlled clinical trials, supports the concepts and recommendations presented in this chapter. ECG examples of ST Elevation Myocardial Infarction (STEMI) STEMI Example…

…Sampling for a suspected sexually transmitted infection — although chlamydia and gonorrhoea can be tested on urine or a self taken vaginal sample without a speculum…

…red meat. The principal evidence supported patterns are Mediterranean type and DASH style diets. Their effects are multidimensional and cannot be adequately inferred from changes…

…an inadequate single drug regimen for prolonged periods. The evidence supports improved blood pressure control and adherence, although prospective outcome trials have not directly established…

…not reverse coronary atherosclerosis. Long term benefit therefore depends on the integration of revascularisation with guideline directed medical therapy and secondary prevention. Clinical Presentation and…