…Depression, schizophrenia, schizoaffective disorder, HIV infection or other circumstances that may affect cessation or treatment monitoring. Single question screening can identify unhealthy drug use requiring…

…Activity Volume and Intensity For adults, the principal preventive target is: 150–300 minutes per week of moderate intensity aerobic activity; or 75–150 minutes…

…is useful for screening and population level risk estimation, but it does not characterize body composition, fat distribution, skeletal muscle mass, physical fitness or individual…

…carotid bruit is an important marker of cardiovascular risk, although the source material does not provide diagnostic sensitivity or specificity for bruit detection. Its pr

…family history remains clinically useful for estimating risk. Pathophysiology and genetic principles Penetrance and variable expression A pathogenic variant does not invariably result in clinical…

…of tendon xanthomas, corneal arcus and xanthelasma. Potential secondary causes of hypercholesterolaemia. The likelihood of a monogenic disorder and the need for family based screening

…European recommendations advise screening adults with confirmed hypertension by measuring renin and aldosterone, although the strongest indications arise in patients with resistant or severe hypertension…

…cardiomyopathy Second degree AV block or third degree AV block (not caused by medications) Stroke within 1 month Preparations for exercise stress testing The laboratory…

…AAA, duplex ultrasound screening for femoropopliteal aneurysms should be considered. Opportunistic screening may also be useful in patients with symptomatic or asymptomatic peripheral arterial disease…

…for the asymptomatic. Symptoms must be investigated wherever in the screening interval the patient happens to be — a recently taken normal smear is no reason…