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De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…selected patients with high ischemic risk and low bleeding risk. These strategies are intended primarily to reduce bleeding rather than to replace the default 12…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…patients with impaired renal function, reflecting both reduced clearance and the high prevalence of structural heart disease in this population. Obesity is associated with lower…

Assessing left ventricular systolic function

…greater precision in the calculation of ejection fraction, and 3D measurements will presumably replace 2D measurements in the future. Cardiac MRI (magnetic resonance imaging) is…

M-mode (motion mode) echocardiography

…mode was previously the dominating modality in echocardiography. Although it has now largely been replaced by 2D echocardiography, it is still used in clinical practice…

A new ECG biomarker for sudden cardiac death

…the slurred terminal portion of the R wave in the high risk morphology, which replaces the sharp negative S wave seen in the low risk…

Sepsis and septic shock: quick reference for the first hour

…same time has a lactate above 2 mmol/L. This combination carries a high mortality [1,2]. Give antibiotics immediately and aim for administration within…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…strong after ACS and coronary stent implantation. ACS is associated with a high risk of platelet driven atherothrombosis, while interruption of antiplatelet therapy after recent…

Ventricular Tachycardia

…undergone a profound paradigm shift. Driven by advanced electroanatomical mapping, high resolution cardiac magnetic resonance (CMR) imaging, and landmark clinical trials, the field has transitioned…

Components and construction of a pacemaker

…requirement is extensive, or if the stimulus threshold (discussed below) is high. When the battery is depleted, the entire system must be replaced. Pacemaker leads…

Bone marrow aspiration and biopsy

Procedurer Aspirate and biopsy answer different questions and do not replace one another: the aspirate shows cellular morphology and provides material for flow cytometry and…

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