…dilated, light unresponsive pupils are indicative of cerebral anoxia or brain death and constitute an adverse prognostic sign. Notably, the presence of dilated, nonreactive pupils…

…show any benefit of urgent angiography. ST elevation in acute transmural myocardial ischemia is discussed in the chapter ST elevations in ischemia and differential diagnoses…

…incidental and asymptomatic finding. The absence of symptoms indicates that the bradycardia is compensated by an increase in stroke volume. Symptomatic bradycardia may present with…

…is indicated in patients with symptoms suggestive of acute myocardial infarction and at least one of the following criteria present: haemodynamic instability or cardiogenic shock…

…the presence of CRT, the type and location of surgery, and the anticipated current pathway. In a pacing dependent patient, inhibition of pacemaker output may…

…heart failure or after myocardial infarction). Ventricular arrhythmias are easier to induce in the presence of arrhythmogenic substrates. A substrate is defined as a physiological…

…partial occlusion of the artery (i.e. coronary blood flow is not completely obstructed). NSTE ACS typically presents with ST segment depressions and/or T…

…supply and demand, without the presence of acute atherothrombosis. Type 3 MI: Describes cardiac death in patients with symptoms suggestive of myocardial ischaemia and presumed…

…The presence of extensive comorbidity may alter the balance between procedural risk and benefit. An early invasive strategy is not recommended when the risks of…

…Symptoms and clinical context The assessment begins with the clinical presentation, including the character and stability of chest discomfort, associated dyspnoea, and the presence of…

…on circulating thrombotic and fibrinolytic factors. Plaque erosion Plaque erosion is increasingly recognized and is present in at least one third of acute coronary syndromes…

…be ignored. The most common situation is when assessing aortic stenosis in the presence of a narrowing of the LVOT (left ventricular outflow tract). Such…

…Pneumothorax is characterized by the presence of free air in the thoracic cavity. While this can occasionally be benign and manifest even in healthy individuals…

…proposed by Smith and colleagues in 2018. This approach seeks to anchor diagnostic and therapeutic decisions in the presence or absence of an acute coronary…

…small amount of serous fluid which acts as a lubricant that prevents friction during ventricular contraction and relaxation. Pericardial effusion is the presence of an…

…presence of wall motion abnormalities in a patient with chest pain strongly suggests myocardial ischemia as the underlying cause of the symptoms. The degree and…

…acute phase protein — a normal ferritin does not exclude iron deficiency in the presence of inflammation Transferrin saturation 15–50 % < 15 % indicates iron deficiency…

…3. Give intravenous calcium in the presence of hyperkalaemic ECG changes or arrhythmia. 4. Shift potassium into the cells with insulin and glucose. Add high…

…adults with elevated blood pressure (BP), in whom absolute cardiovascular risk varies considerably according to age and the presence of concomitant risk factors. In contrast…

…and carotid atherosclerosis tends to be more advanced than in people without diabetes. Carotid disease is also a marker of systemic cardiovascular risk. The presence…

…electrocardiogram (ECG) and the presence of troponin elevation, ACS are classified into unstable angina (UA), non ST segment elevation myocardial infarction (NSTEMI), and ST segment…

…echocardiography. A common question is the presence of right ventricular load. This condition implies that the right ventricle is pressure and/or volume loaded. The…

…progression of right heart failure may indicate the need for inodilator therapy. Furthermore, acute heart failure and cardiogenic shock can present de novo in pregnant…

…factors for HFpEF include hypertension (present in 80% of cases), obesity, type 2 diabetes mellitus, chronic kidney disease (CKD), sedentary lifestyle, and atrial fibrillation (AF)…

…TdP typically present with near syncope, syncope, or cardiac arrest. Before the onset of sustained VT, patients frequently experience PVCs and runs of non sustained…

…the presence of abnormal clinical risk assessment. Low risk PE is characterized by clinical low risk features, negative cardiac biomarkers, and no imaging evidence of…

…Atherosclerotic disease usually evolves over decades. Intimal thickening may be present during the second and third decades of life, while clinical manifestations commonly emerge much…

…epicardial vasomotor abnormalities or structural and functional microvascular disease. Thus, the presence of non obstructive epicardial arteries does not exclude a coronary cause of symptoms…

…function in the presence of persistent congestion is particularly associated with elevated central venous pressure, which is transmitted to the renal veins and can reduce…

…Whether and how PCI was performed. The need for non cardiac surgery. The presence of an indication for oral anticoagulation (OAC). Clinical context and treatment…

…of ST Elevation Several nonischemic conditions can produce ST segment elevations that mimic acute myocardial infarction. Acute pericarditis is a primary differential diagnosis and presents…

…the diagnosis of heart failure is clinically secure and the LVEF measurement is reliable. Nevertheless, these findings increase diagnostic confidence. The presence of symptoms alone…

…may present with chest pain, severe breathlessness, hypoxaemia, rales, or respiratory distress. In patients with HFpEF, acute hypertension is a frequent trigger of decompensation and…

…The presence of ASCVD, peripheral arterial disease or aortic disease. Secondary causes, particularly diabetes, thyroid disease, kidney disease, alcohol excess, dietary factors and relevant medications…

…can either mask or mimic the signs of ischemia or infarction [5]. Prognosis and Survival The presence of LBBB has several implications for patient outcomes…

…in older people and in patients with diabetes. The haemodynamic consequences depend on lesion location, severity, length, the presence of multilevel disease and collateral circulation…

…clinical descriptions. It may be present intermittently during the illness and, in some series, is reported in up to approximately one third of patients. Its…

…setting of acute or chronic heart failure are often better categorised as myocardial injury. Clinical Presentation and Symptoms Patients with Type 2 MI frequently present…

…on the right side can compromise venous return to the right ventricle. Therefore, in the presence of a tamponade, chest compressions have limited efficacy. Furthermore…

…block. Occasionally, right bundle branch block only displays a broad and notched R wave in V1 (instead of two R waves); in that scenario, the…

…In the setting of acute coronary syndrome (ACS), DAPT is used to reduce recurrent myocardial infarction, stent thrombosis and other ischemic events after coronary angiography…

…myocardial oxygen demand and coronary blood supply. Stress increases myocardial oxygen requirements, principally through increased heart rate and contractility. In the presence of a flow…

…severe pulmonary stenosis, alongside right ventricular hypertrophy (RVH) and right atrial enlargement [8]. RAD is present in most cases of significant RVH, although it is…

…Epicardial and microvascular angina can coexist, and this combination is associated with a worse prognosis. VA may occur in the presence of obstructive coronary artery…

…the behavior of the pacemaker at low and high heart rate, the behavior of the pacemaker in the presence and absence of intrinsic cardiac activity…

…be seen in arrhythmogenic tumors of the myocardium; in these cases, the tumor can debut with ventricular arrhythmias that result in asystole and sudden death…

…and infarction. Symptoms – Patients with acute myocardial infarction may present with typical ischemic chest pain, or with dyspnea, nausea, unexplained weakness, or a combination of…

…been extremely valuable. Echocardiography is used to assess the morphology of valves, the presence of vegetations, hemodynamic status, and the extent of endocarditis. Endocarditis gives…

…in order to assess the presence of myocardial ischemia, evaluate angina pectoris, evaluate exercise performance, evaluate the effect of interventions and medications, and prognosticate survival…

…Presence of potentially serious arrhythmias – due to the risk of circulatory collapse. Decompensated heart failure – due to the risk of circulatory collapse and arrhythmias Pulmonary…

…difficult in the presence of left bundle branch block. This is because left bundle branch block causes substantial changes in left ventricular depolarization and repolarization…

…R wave in V5 and V6. Secondary ST T changes occur invariably in the presence of LBBB. The following ECG criteria and characteristics are used…

…Unstable Angina presents with clinical and/or electrocardiographic signs of myocardial ischemia but lacks this biomarker elevation. With the ubiquitous adoption of hs cTn assays…

…establish: The time of symptom onset and the rate of progression The location and severity of pain The presence and extent of sensory loss Any…

…defines: The presence and severity of left main stenosis Ostial, shaft or distal bifurcation involvement Disease in the left anterior descending and left circumflex arteries…

…number of lesions, their location, and specific characteristics such as bifurcations, chronic total occlusions (CTOs), calcification, and thrombus presence. These factors are weighted and summed…

…of the diagnosis. 3. Palpate the pulses and measure the ankle brachial index with Doppler. 4. Culture only in the presence of clinical signs of…

…presence of albuminuria: check the potassium, calcium, phosphate, PTH, haemoglobin and bicarbonate , review the medication list (metformin, NSAIDs, RAAS blockade, gabapentin, direct oral anticoagulants) and…

…present and whether left ventricular systolic function is depressed or preserved Whether hypotension is present Whether an accessory pathway is suspected, particularly before administration of…

…HFrEF. Clinical evaluation should define: The severity of symptoms and functional limitation. Evidence of congestion or fluid retention. The presence of precipitating or aggravating conditions…