…be considered. Effective lipid lowering improves survival and reduces cardiovascular mortality in patients with coronary artery disease irrespective of the baseline cholesterol concentration. Intensive statin…

…Recent intracranial haemorrhage without a fresh assessment of benefit and risk. An inability to attend for sampling and follow up — relative, but in practice decisive…

…better alternative. Follow up At an eGFR below 60, or in the presence of albuminuria: check the potassium, calcium, phosphate, PTH, haemoglobin and bicarbonate , review…

…Schedule the test in the morning, preferably starting between 08:00 and 09:00 , with the patient fasting or having had a light breakfast according…

…with co oximetry Follow up of pH in, for example, ketoacidosis A venous sample is often sufficient if respiratory failure is not suspected Shock with…

…In a patient with normal baseline cTn, type 4a MI is defined by: cTn greater than 5 times the 99th percentile upper reference limit; and…

…fit and independent generally benefit from guideline directed blood pressure treatment similar to that used in younger adults, provided it is tolerated. Patients with functional…

…In older patients delirium is often multifactorial. 7. Start non pharmacological treatment immediately , in parallel with the investigation. 8. Document the diagnosis and communicate it…

…mutations in LMNA , MYH7 , and TNNT2 [39] . Consequently, current guidelines recommend a 3 generation family history and consideration of genetic testing for all patients with…

…and HFpEF (≥50%) [1] [2] . Crucially, contemporary definitions distinguish HFpEF from "Heart Failure with improved EF" (HFimpEF). HFimpEF refers to patients with a historical baseline…