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Bempedoic Acid: Evidence and Clinical Use

…double blind, placebo controlled study of 13,970 patients at high cardiovascular risk who were unable or unwilling to take statins. Approximately 70% were in…

Clinical application of ECG in chest pain & acute myocardial infarction

…in the size of the thrombus. This means that a patient who experienced chest pain at home may be asymptomatic during the assessment in the…

🟠 HAS-BLED Score Calculator

…serves as a tool to identify patients who may require more careful monitoring and management of modifiable risk factors. The HAS BLED score has demonstrated…

Levosimendan (Simdax, Simendan) in acute heart failure

…All patients with severe acute heart failure who receive levosimendan should be monitored invasively (e.g. arterial line, PiCCO, central venous catheter). The hemodynamic effects…

Antibiotic dosing in renal impairment: quick reference

…73 m². Recalculate in patients who are markedly larger or smaller than average. Higher doses may be required in the critically ill patient. Intravenous antibiotics…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…declined over time due to the advent of more efficacious agents with wider therapeutic to toxic windows, and its routine use in adult patients is…

🟠 Ticagrelor (Brilinta, Brilique)

…taken at the next regular time. Use with caution in patients with asthma/chronic obstructive pulmonary disease (COPD). Dyspnea has been reported in patients treated…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…In selected patients, P2Y12 inhibitor monotherapy may be used as a de escalation strategy after a period of DAPT. The therapeutic objective is to reduce…

🟠 Clonidine

…these patients should be carefully balanced against the potential risks resulting from hypotension. • Withdrawal of clonidine may lead to rebound hypertension. Withdraw slowly. • Simultaneous use…

Neutropenic fever: quick reference for emergency management

…and local care programmes use 38.5 degrees instead. Follow the local definition where one exists, but a neutropenic patient who is clinically unwell must…

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