…specified by the guideline. PCSK9 inhibitors are also relevant in statin intolerant patients who remain above goal despite alternative lipid lowering therapy. Evolocumab and alirocumab…

…neutropenic patient who is clinically unwell must be managed as an emergency even at a lower temperature. Suspect neutropenia in anyone who has received cytotoxic…

…compared to conventional CPR in patients with refractory out of hospital cardiac arrest. Patients aged 18 to 70, who received bystander CPR and initially presented…

…However, most clinicians who encounter patients with pacemakers only have access to conventional surface ECGs. Being able to assess pacemaker function and perform troubleshooting should…

…be counteracted with simultaneous administration of norepinephrine. All patients with severe acute heart failure who receive levosimendan should be monitored invasively (e.g. arterial line…

…be preferable in patients aged ≥85 years, those with symptomatic orthostatic hypotension, moderate to severe frailty, or very old or frail patients who may not…

…and ongoing evaluations of patients in cardiac arrest or after return of spontaneous circulation (ROSC). A brisk, reactive pupil generally indicates an intact brainstem and…

…bundle branches. Individuals with ischemic heart disease (or myocardial infarction) who present with right bundle branch block typically also have a fascicular block. This condition…

…despite three or more antihypertensive drugs from different classes at maximally tolerated doses, including a diuretic appropriate for kidney function. In patients with an estimated…

…than in patients who remain in sinus rhythm. Several mechanisms may account for apparent ischaemic electrocardiographic changes during rapid AF. ST segment depression or T…