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🟠 Prasugrel (Effient, Efient, Prasita)

…Maintenance dose : 5 mg once daily. Rationale: Patients in this age group have higher bleeding risk and increased exposure to the active metabolite of prasugrel…

Secondary Hypertension: When and How to Investigate

…it is an indicator of increased cardiovascular risk and a setting in which secondary hypertension is relatively common. Patients presumed to have resistant hypertension should…

Warfarin therapy

…what happens when the INR runs away or the patient bleeds. In Sweden the treatment is usually managed from an anticoagulation clinic with dosing support…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

… an accelerating pattern, with increasing frequency or severity; angina that awakens the patient from sleep. Patients receiving modified antiplatelet therapy require clinical surveillance for both…

Ectopic atrial rhythm (EAT), atrial tachycardia (AT) & multifocal atrial tachycardia (MAT)

…uncommon unless the patient is receiving digoxin. The ventricular rate is regular, typically ranging from 100 to 250 beats per minute in atrial tachycardia and…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…also utilized for ventricular rate control in atrial fibrillation, particularly when other therapeutic options cannot be pursued. Patients receiving digoxin may present with symptoms of…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…For a patient who experiences a recurrent atherothrombotic event while receiving maximally tolerated statin therapy, an LDL C goal below 1.0 mmol/L (<40…

Inclisiran and Emerging Lipid-Lowering Agents

…equivalent who were receiving statins, inclisiran produced a further reduction in LDL C of approximately 50%. The effect was consistent in patients with and without…

Lipid-Lowering Therapy: Statins as First-Line Treatment

…In patients who experience a recurrent atherothrombotic or cardiovascular event within 2 years while receiving maximally tolerated statin based treatment, an LDL C goal below…

Acquired QT Prolongation and Drug-Induced Arrhythmia

…Clinicians should maintain a high index of suspicion for drug induced arrhythmias in patients receiving agents known to alter the electrical properties of the heart …

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