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Secondary Hypertension: When and How to Investigate

…the clinical picture. A 24 hour urine collection for electrolytes can be used to quantify sodium and potassium intake, preferably while the patient is receiving…

Warfarin therapy

…effect is wanted and the patient is also receiving LMWH, for example in newly diagnosed venous thromboembolism. 1. Check the INR before the first dose…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

… the type of revascularization; stent related risk; whether long term oral anticoagulation is required; tolerance of treatment during the initial months. Patients with HBR are…

Ectopic atrial rhythm (EAT), atrial tachycardia (AT) & multifocal atrial tachycardia (MAT)

…followed by a QRS complex; atrioventricular block is uncommon unless the patient is receiving digoxin. The ventricular rate is regular, typically ranging from 100 to…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…Diagnostics Electrocardiography and Electrophysiology Electrocardiographic evaluation of patients receiving digoxin reveals specific electrophysiologic profiles. Digoxin's autonomic actions largely slow the sinus node discharge rate…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…appropriate first line pharmacological option when a patient is unable to tolerate any statin regimen. The treatment sequence for patients with chronic coronary syndrome is:…

Inclisiran and Emerging Lipid-Lowering Agents

…equivalent who were receiving statins, inclisiran produced a further reduction in LDL C of approximately 50%. The effect was consistent in patients with and without…

Lipid-Lowering Therapy: Statins as First-Line Treatment

…In treatment naïve patients unlikely to achieve the LDL C goal with statin therapy alone, initiation of high intensity statin plus ezetimibe during hospitalization should…

🟠 Prasugrel (Effient, Efient, Prasita)

…UA/NSTEMI patients undergoing coronary angiography within 48 hours of hospital admission, the loading dose should be administered at the time of PCI. Patients should…

Acquired QT Prolongation and Drug-Induced Arrhythmia

…index of suspicion for drug induced arrhythmias in patients receiving agents known to alter the electrical properties of the heart (inducing QRS or QT prolongation…

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