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Digoxin: Dosing, Therapeutic Range and Toxicity Management

…evaluation of patients receiving digoxin reveals specific electrophysiologic profiles. Digoxin's autonomic actions largely slow the sinus node discharge rate, shorten atrial refractoriness, and prolong…

Warfarin therapy

…effect is wanted and the patient is also receiving LMWH, for example in newly diagnosed venous thromboembolism. 1. Check the INR before the first dose…

Acquired QT Prolongation and Drug-Induced Arrhythmia

…patients receiving agents known to alter the electrical properties of the heart (inducing QRS or QT prolongation) or causing electrolyte abnormalities, such as thiazide and…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…dL), and at least a 50% reduction from baseline. For a patient who experiences a recurrent atherothrombotic event while receiving maximally tolerated statin therapy, an…

Inclisiran and Emerging Lipid-Lowering Agents

…and lipoprotein(a) are variable or modest. In phase III studies involving patients with ASCVD or at least one ASCVD risk equivalent who were receiving…

Lipid-Lowering Therapy: Statins as First-Line Treatment

… and A reduction of at least 50% from baseline. In patients who experience a recurrent atherothrombotic or cardiovascular event within 2 years while receiving maximally…

Secondary Hypertension: When and How to Investigate

…24 hour urine collection for electrolytes can be used to quantify sodium and potassium intake, preferably while the patient is receiving a stable diuretic dose…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…increasing frequency or severity; angina that awakens the patient from sleep. Patients receiving modified antiplatelet therapy require clinical surveillance for both recurrent ischemia and bleeding…

Ectopic atrial rhythm (EAT), atrial tachycardia (AT) & multifocal atrial tachycardia (MAT)

…unless the patient is receiving digoxin. The ventricular rate is regular, typically ranging from 100 to 250 beats per minute in atrial tachycardia and less…

🟠 Prasugrel (Effient, Efient, Prasita)

…Patients receiving medications that increase bleeding risk, including oral anticoagulants, clopidogrel, NSAIDs, or fibrinolytics. For patients with active bleeding requiring reversal of prasugrel's pharmacological…

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