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Colchicine and Anti-inflammatory Therapy in Coronary Disease

…rather than lipid lowering. Other anti inflammatory strategies have produced less favourable results. Canakinumab, a monoclonal antibody directed against interleukin 1β, provided proof of…

Neutropenic fever: quick reference for emergency management

…neutropenic patient who is clinically unwell must be managed as an emergency even at a lower temperature. Suspect neutropenia in anyone who has received cytotoxic…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…compared to conventional CPR in patients with refractory out of hospital cardiac arrest. Patients aged 18 to 70, who received bystander CPR and initially presented…

Hypertension: Initial Combination Therapy and Drug Selection

…nonpharmacological management should be actively implemented. Adults with blood pressure ≥140/90 mmHg should receive both lifestyle and antihypertensive drug therapy. For grade 1 hypertension…

PCSK9 Inhibitors: Indications, Efficacy and Access

…C by approximately 50–60%, including in patients receiving background statin therapy and in those unable to tolerate statins, provided that hepatic LDL receptor expression…

Levosimendan (Simdax, Simendan) in acute heart failure

…be counteracted with simultaneous administration of norepinephrine. All patients with severe acute heart failure who receive levosimendan should be monitored invasively (e.g. arterial line…

Supraventricular and intraventricular conduction defects in myocardial ischemia and infarction

…near the ventricular cavity, and it may to some extent receive oxygen from the blood in the ventricular cavity. The right bundle branch then runs…

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…and potential adverse effects, consideration should be given to initiating therapy with the patient hospitalized and monitored for at least several days. Intravenous Loading For…

Principles and Preparations for Echocardiographic Examinations

…Cardiology) Preparations for the examination Patients referred for echocardiography should receive information regarding the conduction of the examination. Some patient engagement is required to obtain…

Sinoatrial arrest & sinoatrial pause (sinus pause / arrest)

…be normal (QRS duration <0.12 s), because both bundle branches receive the impulse and spread it. If the impulse is discharged distal to the…

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