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Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…of a PCSK9 inhibitor. Place in lipid lowering therapy General treatment sequence High intensity statin therapy remains the foundation of lipid lowering treatment for patients…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…drugs have not been shown to improve long term cardiovascular outcomes in CCS. General strategy For most patients, initial therapy consists of a beta blocker…

PCSK9 Inhibitors: Indications, Efficacy and Access

…is generally: High intensity statin therapy at the highest tolerated dose. Addition of ezetimibe if the LDL C target is not achieved. Addition of a…

CME: How dietary fat affects coronary arteries, LDL cholesterol and body weight

…mortality due to stopping statins. There are three main questions discussed in media, blogs and on social plattforms: Is high cholesterol a true cause of…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…the patient from sleep. Patients receiving modified antiplatelet therapy require clinical surveillance for both recurrent ischemia and bleeding. The source material does not specify a…

Hyperkalaemia: quick reference for emergency treatment

…rising potassium is usually more dangerous than a corresponding stable chronic value [4]. The grading must not be used mechanically. A patient with a plasma…

Acute Pulmonary Embolism: Risk Stratification and Reperfusion

…Syncope is particularly important as a marker of potentially severe disease. The presence of haemodynamic instability places the patient in the high risk category and…

Basic cardiac pacing, pacemaker functions and settings

…be tailored to the patient's needs. Programming is done through an external device that communicates wirelessly with the pacemaker. A wide range of settings…

Coronary Artery Calcium Scoring: Prognostic Use in Practice

…to initiate or intensify preventive therapy is uncertain. Prevention guidelines support its use in selected individuals at intermediate risk, rather than as a universal population…

Risk Factor Modification: The Evidence Base for Primary Prevention

…Patients with manifest clinical disease are at high risk of progression and generally require all appropriate evidence based measures, including drug treatment and therapeutic lifestyle…

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