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Soft tissue corticosteroid injection

…a tool to make rehabilitation possible, not an alternative to it. See the separate guide to joint aspiration and injection. Indications Condition Injection site Comment…

Other ECG changes in ischemia and infarction

…Q waves and guidelines do not state any ECG criteria specific to R wave progression. Figure 1. Pathological R wave progression is indicative of previous…

Cardiovascular Risk in Women: Sex-Specific Factors

…reproductive and pregnancy related history. Female specific or female predominant factors associated with later cardiovascular risk include: Premature menopause Premature ovarian insufficiency Hypertensive disorders of…

Secondary Hypertension: When and How to Investigate

…resistance. Hypokalaemia should not be permitted when assessing dietary electrolyte intake, because it can increase blood pressure and may affect interpretation of the clinical picture…

ECG Criteria for STEMI (ST Elevation Myocardial Infarction)

…acute pericarditis is typically diffuse, involving all leads except aVR and often V1, and does not correspond to a specific coronary anatomic distribution [4, 5]…

ACE Inhibitor Cough and Angioedema: Practical Management

…accumulation of bradykinin. ACE is responsible for metabolizing bradykinin and other tachykinins, such as substance P. When ACE is inhibited, the resulting accumulation of these…

Chest Pain in the Emergency Department: Diagnostic Pathways

…injury leads to release of cardiac troponin, but troponin elevation is not specific for myocardial infarction. Other conditions may produce cardiomyocyte injury and elevated troponin…

Familial and Genetic Screening in Premature Cardiovascular Disease

…severity and manifestations of disease may differ substantially among carriers. Consequently, a normal examination or cardiac investigation at one point in time does not reliably…

Fractional Flow Reserve and Non-Hyperaemic Pressure Ratios

…in the context of the clinical presentation and other findings. A reduced CFR may occur with angiographically insignificant epicardial disease because of abnormalities in the…

Edrophonium test

…The test has a sensitivity of around 60 % and is not specific: motor neurone disease, myopathies and Lambert–Eaton syndrome may also give a positive…

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