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🟠 Aspirin (Acetylsalicylic acid)

…to plasma albumin, but the therapeutic effect remains unchanged. Sulfonylureas: Salicylates may potentiate the hypoglycemic effect of sulfonylureas, possibly due to reduced binding to serum…

Urinary alkalinisation

…Heart failure, pulmonary oedema and other conditions with a high risk of fluid overload — a relative contraindication requiring invasive monitoring and slower administration. Significant metabolic…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…The cardiovascular burden of CKD extends beyond CAD to peripheral arterial disease, cerebrovascular disease, valvular heart disease, heart failure, atrial fibrillation, and other arrhythmias or…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…effects of contrast exposure and other ischaemic or nephrotoxic stresses. The kidney is particularly vulnerable to toxic injury because of its high blood flow and…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…use has declined over time due to the advent of more efficacious agents with wider therapeutic to toxic windows, and its routine use in adult…

Cardiac arrest due to electrolyte imbalance

…duration): Due to cellular adaptations, rapid correction carries the risk of inducing osmotic demyelination syndrome (ODS). It is therefore recommended to raise serum sodium by…

Other ECG changes in ischemia and infarction

…transmural ischemia may transiently increase the amplitude of the R waves. This is believed to be due to delayed (and thus electrically unopposed) depolarization in…

Acute exacerbation of COPD: quick reference

…the COPD exacerbation apart from many other causes of acute dyspnoea: oxygen must be titrated cautiously and the blood gas determines the need for ventilatory…

🟠 Ticagrelor (Brilinta, Brilique)

Info Table 1 provides a summary of the indications, contraindications, dosage, administration, warnings, precautions, and other relevant information for the drug Ticagrelor . Table 1 Summary…

Familial and Genetic Screening in Premature Cardiovascular Disease

…a 50% risk of transmitting the relevant variant to each child. However, other inheritance patterns, de novo variants, incomplete penetrance and variable phenotypic expression complicate…

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