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Neutropenic fever: quick reference for emergency management

…pain or a rapid deterioration in general condition may be the only signs of infection. Corticosteroids and other immunosuppressive treatments can blunt the febrile response…

Early repolarization on ECG: when guidelines confuse ECG criteria

…QRS duration is <120 ms. Panel B in Figure 5 below shows another example of early repolarization. Readers interested in ST segment elevation differential diagnoses…

Acute exacerbation of COPD: quick reference

…Lathundar Key messages Two things set the COPD exacerbation apart from many other causes of acute dyspnoea: oxygen must be titrated cautiously and the blood…

Acute Pulmonary Embolism: Risk Stratification and Reperfusion

…pulmonary vascular obstruction is accompanied by limited cardiopulmonary reserve or other adverse comorbidity. The classification of acute PE comprises four clinically useful groups: High risk…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…from selected populations, frequently with low or intermediate ischemic risk and under representation of patients with STEMI or other very high risk features. Noninferiority studies…

Familial and Genetic Screening in Premature Cardiovascular Disease

…Familial and genetic screening in cardiovascular medicine is the systematic assessment of relatives and other individuals who may carry an inherited predisposition to cardiovascular disease…

Alcohol withdrawal and delirium tremens: quick reference

…against clinical effect. 2. Parenteral thiamine early , preferably before or at the same time as carbohydrate administration. 3. Rapid identification of seizures, delirium tremens, infection…

Urinary alkalinisation

…measure: early and generous fluid administration. The benefit of alkalinisation over fluids alone is disputed and practice differs between units. Poisoning with other weak acids…

Atropine: Dosing in Bradycardia and Its Limitations

…bradycardia in the early hours following infarction may be associated with hemodynamic compromise. More broadly, bradyarrhythmic arrest and asystole represent severe manifestations of impulse generation…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…characterized by persistently elevated plasma low density lipoprotein cholesterol (LDL C) from early life and a consequent excess risk of premature atherosclerotic cardiovascular disease (ASCVD)…

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