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ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…Other causes include acute mechanical complications—particularly ventricular septal defect (VSD) and papillary muscle rupture with acute severe mitral regurgitation—predominant right ventricular (RV) infarction…

Acute coronary syndrome: quick reference for loading doses and time targets

…dangerous differential diagnoses [1,2]. STEMI and other ECG patterns suggesting acute coronary occlusion are time dependent conditions. The decision on immediate reperfusion is based…

Hypertensive Emergency and Urgency: Differentiation and Treatment

…acute HMOD, although other guidance emphasizes that no single BP threshold is diagnostically sufficient: the presence of ongoing acute organ injury is decisive. The pathophysiology…

Diagnostic Criteria for Acute Myocardial Infarction: Cardiac troponins, ECG & Symptoms

…plaque. Upon such damage, the plaque exposes highly thrombogenic materials which activate circulating platelets and coagulation factors, which results in thrombus formation (Figure 1). Disruption…

🟠 Aspirin (Acetylsalicylic acid)

…interactions Anticoagulants, thrombolytics, or other platelet aggregation inhibitors: Salicylates inhibit platelet function and enhance the effect of anticoagulants, increasing bleeding risk. Monitor coagulation. Cyclosporine, tacrolimus…

Dietary Patterns and Cardiovascular Outcomes

…and apolipoproteins, endothelial function, systemic inflammation, liver fat synthesis, adiposity, thrombosis and coagulation, cardiac function, satiety, appetite, the gut microbiome and metabolic expenditure. Food processing…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…severe, myocardial necrosis. It most commonly reflects atherothrombosis: disruption of an atherosclerotic plaque followed by platelet activation and coagulation, with formation of an intraluminal thrombus…

Classification of Acute Coronary Syndromes (ACS) & Acute Myocardial Infarction (AMI)

…occur when atherosclerotic plaques disrupt, resulting in the activation of thrombocytes and coagulation factors causing the formation of a thrombus. Such a thrombus can cause…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…rivaroxaban and edoxaban. Check every 6 months 15 30 Dabigatran contraindicated. The other DOACs are possible according to FASS, but the documentation is insufficient; check…

Bone marrow aspiration and biopsy

…Previous pelvic irradiation on the intended side (yields fibrotic, unrepresentative marrow — choose the other side). A patient who cannot lie still — plan for sedation rather…

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