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Blood pressure

…with the same risk as manifest hypertension. Non dipping: a nocturnal fall in pressure of < 10% of the daytime value; an independent risk marker…

CPAP and non-invasive ventilation (NIV)

…Choice of method and settings Condition Method Starting pressure Escalation Oxygen target : : : : : Cardiogenic pulmonary oedema CPAP 5–7.5 cmH₂O Increase in steps of 2…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…further increases blood pressure. Non traditional cardiovascular mechanisms include: Uraemia associated inflammation Oxidative stress Vascular dysfunction Promotion of vascular calcification Albuminuria and proteinuria Neurohormonal activation…

Cardiac arrest due to hypoxia and asphyxia

…reduced partial pressure of oxygen in the blood. Asphyxia is characterized by insufficient ventilation, leading to hypoxia. Etiologies of hypoxic cardiac arrest : Trauma and injuries…

Inotropes and vasopressors: doses, indications, contraindications and effects

…Nitroprusside Figure 1. The approximate position of each drug according to its vasoconstrictor effect (vertical axis) and its positive inotropic effect (horizontal axis). Grey =…

Pulmonary Hypertension: Classification and Treatment Principles

…most common risk factor for PH. It produces postcapillary PH through elevation of left atrial and pulmonary venous pressure. In some patients, chronic postcapillary pr

Cardiovascular Risk Assessment with SCORE2 and SCORE2-OP

…competing risk of death from non cardiovascular causes, an important consideration in older populations. Risk prediction is particularly relevant in adults with elevated blood pressure …

Cardiac tamponade causing cardiac arrest

…The increased pressure causes compression of the atria and the ventricles (particularly the former). Even small pressure elevations on the right side can compromise venous…

Opioid therapy in severe pain

…lower doses than for pain). An opioid is rarely the right choice in nociplastic or neuropathic pain, in chronic non cancer pain, or in headache…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…the balance between reduction in ischaemic events and possible infectious or other non cardiovascular adverse outcomes. Mechanisms of action Colchicine Colchicine appears to exert several…

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