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Blood pressure

…raised outside it — associated with the same risk as manifest hypertension. Non dipping: a nocturnal fall in pressure of < 10% of the daytime value…

CPAP and non-invasive ventilation (NIV)

…are two different treatments with different physiology, and the commonest source of error is confusing them. CPAP delivers a constant pressure that recruits alveoli and…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…renal function further increases blood pressure. Non traditional cardiovascular mechanisms include: Uraemia associated inflammation Oxidative stress Vascular dysfunction Promotion of vascular calcification Albuminuria and proteinuria…

Cardiac arrest due to hypoxia and asphyxia

…al. and Safar et al. The majority of all asphytic cardiac arrests begin with PEA and progress to asystole. Shockable rhythms (ventricular fibrillation [VF], ventricular…

Inotropes and vasopressors: doses, indications, contraindications and effects

…induce vasoconstriction and raise the mean arterial pressure (MAP). Inotropes increase myocardial contractility. There are several synthetic and endogenous agents with inotropic and vasopressor effects…

Pulmonary Hypertension: Classification and Treatment Principles

…most common risk factor for PH. It produces postcapillary PH through elevation of left atrial and pulmonary venous pressure. In some patients, chronic postcapillary pr

Cardiovascular Risk Assessment with SCORE2 and SCORE2-OP

…competing risk of death from non cardiovascular causes, an important consideration in older populations. Risk prediction is particularly relevant in adults with elevated blood pressure …

Cardiac tamponade causing cardiac arrest

…the right ventricle. Therefore, in the presence of a tamponade, chest compressions have limited efficacy. Furthermore, administering large tidal volumes might inadvertently elevate intrathoracic pressures…

Opioid therapy in severe pain

…lower doses than for pain). An opioid is rarely the right choice in nociplastic or neuropathic pain, in chronic non cancer pain, or in headache…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…with previous myocardial infarction and residual inflammation, defined by hsCRP ≥2 mg/L, it produced a modest reduction in a composite of cardiovascular death, non…

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