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Colchicine and Anti-inflammatory Therapy in Coronary Disease

…and acute coronary syndromes have important inflammatory components. Inflammation contributes to atherothrombosis through activation of innate immune pathways, cytokine signalling and recruitment of inflammatory cells…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…debris, modern vascular biology has redefined atherosclerosis as a dynamic, immune mediated fibroproliferative response to endothelial injury [2] . The process initiates with endothelial dysfunction, a…

Heart Failure with Reduced Ejection Fraction (HFrEF)

…protective effect of adiposity. Etiology and underlying causes The etiology of HFrEF is broadly dichotomized into ischemic and non ischemic causes, a distinction that fundamentally…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…typically platelet rich and less occlusive, often presenting clinically as Non ST Elevation Myocardial Infarction (NSTEMI) rather than STEMI [4] . Calcified Nodules: A less common…

NSTEMI (Non-ST Elevation Myocardial Infarction) & Unstable Angina: Diagnosis, Criteria, ECG, Management

ECG Myocardial ischemia and infarction Non ST Elevation Acute Coronary Syndromes (NSTE ACS): Non ST Elevation Myocardial Infarction (NSTEMI) and Unstable Angina (UA) The focus…

ApoB and Non-HDL Cholesterol in Cardiovascular Risk Assessment

…and other triglyceride rich particles Thus, non HDL C provides a broader estimate of atherogenic cholesterol than LDL C alone. It is particularly informative when…

Myocardial Infarction with Non-Obstructive Coronary Arteries: Causes, Work-up and Management

Myocardial ischemia and infarction Definition and clinical concept Myocardial infarction with non obstructive coronary arteries (MINOCA) describes a clinical presentation in which the patient has…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…coronary microvascular dysfunction or vasospasm. A normal or non obstructive coronary anatomy does not necessarily exclude an ischaemic mechanism. Clinical assessment and estimation of pre…

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