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Statin Intolerance and Statin-Associated Muscle Symptoms

…should not be combined with statins because it alters statin absorption, hepatic uptake and disposition. Clinical presentation and symptoms Typical SAMS consists of: Symmetric muscle…

Post-Infarction Mechanical Complications: Ventricular Septal, Free-Wall, and Papillary Muscle Rupture

…rupture (VSR), producing an acute left to right shunt. Ventricular free wall rupture, producing haemopericardium and cardiac tamponade. Papillary muscle rupture, producing acute severe mitral…

Reduction of dislocations

Procedurer A dislocation is reduced with muscle relaxation, not with force. The methods that work best exploit time, gravity and slow movement; those that fail…

Cardiac troponin I (TnI) and T (TnT): Interpretation and evaluation in acute coronary syndromes

…and a faster release kinetics. This may explain higher peak levels of cTnI compared with cTnT. Normal values (reference values) URL (upper reference limit) : The…

Anthropometric measurements

…of the individual: it does not distinguish muscle from fat and takes no account of fat distribution. Waist circumference and the waist–hip ratio predict…

Renal parameters

…C based eGFR With an atypical muscle mass, or to confirm a creatinine based value The mean of creatinine and cystatin C The most reliable…

🟠 Clevidipine

…calcium channel blocker. Clevidipine is highly selective for vascular smooth muscle cells and has little or no effect on myocardial contractility or conduction. Clevidipine reduces…

🟠 Nicardipine

…of smooth muscle cells. As compared with nitroprusside, nicardipine induces relatively greater venodilation than arteriolar dilation. Effects Nicardipine causes dilation of the coronary and systemic…

Acute Limb Ischaemia: Recognition and Urgent Management

…an upper or lower limb that causes tissue metabolic requirements to exceed available blood flow. The resulting ischaemia threatens skeletal muscle and peripheral nerves and…

P-wave, PR interval, PR segment: physiology, criteria & ECG findings

…a reflection of right atrial depolarization and the second half is a reflection of left atrial depolarization. This is shown in Figure 3 (upper panel)…

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